Manhattan Reproductive Medicine is a boutique fertility practice located at 159 East 74th Street, Suite C, New York, New York 10021, in the heart of the Upper East Side. The practice is led by Dr. Hanna Jesionowska, a reproductive endocrinologist whose work is reflected at hannajesionowskamd.com. The Upper East Side address places the clinic within walking distance of Lenox Hill and within a neighborhood long known for its concentration of specialist physicians and research-affiliated medical offices. Patients coming from the East Side can often reach the office on foot or via the 4/5/6 subway lines. For the broader New York State fertility landscape, visit the New York fertility clinic directory.
Physicians and Clinical Team
Dr. Hanna Jesionowska is the central figure at Manhattan Reproductive Medicine, and her personal approach to care is a defining characteristic of this practice. In a city where many fertility centers operate as large multi-physician networks with rotating coverage, Manhattan Reproductive Medicine's boutique structure means patients work closely with Dr. Jesionowska throughout their diagnostic evaluation and treatment cycle.
Reproductive endocrinologists like Dr. Jesionowska complete a four-year OB/GYN residency followed by a three-year fellowship in reproductive endocrinology and infertility (REI), earning board certification from the American Board of Obstetrics and Gynecology. This specialized training equips them to manage complex infertility presentations, recurrent pregnancy loss, and hormonal disorders affecting fertility. Patients are encouraged to contact the practice to confirm current physician availability and whether the clinic is accepting new patients.
Services and Treatments
Manhattan Reproductive Medicine offers a range of fertility diagnostic and treatment services consistent with a specialized Upper East Side reproductive endocrinology practice:
- Comprehensive fertility evaluation for both partners
- In vitro fertilization (IVF) with fresh and frozen embryo transfer
- Intrauterine insemination (IUI)
- Ovulation induction and timed intercourse cycles
- Egg freezing (oocyte cryopreservation) for elective fertility preservation
- Embryo cryopreservation and frozen embryo transfer (FET)
- Preimplantation genetic testing (PGT-A, PGT-M, PGT-SR)
- Hormonal testing including AMH, FSH, estradiol, and antral follicle count
- Evaluation and management of recurrent pregnancy loss
- Donor egg and donor sperm coordination
- Polycystic ovary syndrome (PCOS) evaluation and treatment
- Endometriosis-related fertility management
Laboratory and Success Rates
Boutique IVF practices in Manhattan often partner with high-complexity reproductive laboratories nearby or have dedicated in-office laboratory facilities. The quality of embryo culture, sperm preparation, and cryopreservation procedures directly affects IVF success rates. Patients considering this practice should ask during consultation about the embryology laboratory setup, ICSI capabilities, and experience with PGT biopsies.
Patients should review the most current cycle-level data published by the CDC's ART Surveillance program and the SART Clinic Summary Report.
Patient Experience
Patients at boutique Upper East Side practices frequently cite the personalized attention as a significant advantage. Unlike large fertility networks where a patient may consult with one physician but have monitoring appointments and retrievals performed by others, a single-physician practice typically offers greater continuity of care. This matters to many patients navigating emotionally demanding treatment cycles.
The 74th Street location is in a quiet residential and professional stretch of the Upper East Side. Nearby crosstown buses and the Lexington Avenue subway corridor make the location convenient for patients commuting from other Manhattan neighborhoods, the Bronx, or Long Island City in Queens. Parking, while limited in this neighborhood, is available in nearby garages.
For patients who value a discreet, private clinical environment over the infrastructure of a large hospital-affiliated network, a boutique practice like this one can be a strong fit.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
Insurance and Financing
New York State has one of the most comprehensive fertility insurance mandates in the country. State law requires large group health insurance plans to cover infertility diagnosis and treatment, including IVF. Covered services typically include a specified number of IVF cycles, IUI, and related diagnostic procedures. However, mandate coverage specifics vary by plan type — HMO, PPO, and self-insured employer plans (governed by ERISA) may differ. Patients should request a benefits verification from the clinic's financial coordinator before beginning treatment.
For costs not covered by insurance — including donor egg cycles, some genetic testing, and medications not on formulary — the practice likely offers or can refer patients to third-party financing options. The boutique practice setting may also allow for greater flexibility in discussing payment arrangements directly.
Frequently Asked Questions
Is Manhattan Reproductive Medicine a good choice for someone who wants a more personal experience? Yes. The boutique, single-physician model of this practice is specifically suited to patients who want to work directly with their doctor throughout treatment rather than cycling through a large team. This type of practice typically offers more direct communication and individualized protocol design.
Does the practice handle egg freezing for elective fertility preservation? Elective egg freezing is a common service at Manhattan fertility practices. Patients in their late twenties or thirties who are not yet ready to pursue pregnancy can bank mature oocytes for potential future use. Ask the clinic about their specific egg freezing protocols, storage arrangements, and pricing.
Does New York's fertility mandate cover IVF at this clinic? New York's mandate applies to most large group insurance plans offered in the state. Patients should confirm that their specific plan includes IVF coverage and that this clinic is in-network before scheduling. Self-insured employer plans may not be subject to state mandates.
How do I book a first consultation? Contact the practice directly by phone or through the website at hannajesionowskamd.com to request a new patient appointment. Come prepared with any prior fertility testing results, OB/GYN records, and a list of medications and supplements you are currently taking.
