NYU Langone Fertility Center is the reproductive medicine program of NYU Langone Health, one of New York City's leading academic medical centers, located at 159 E 53rd Street, Floor 3, in Midtown Manhattan. The center combines the clinical rigor and research resources of a major academic institution with a patient-facing practice that earns a 4.4-star rating from nearly 285 reviewers. NYU Langone's fertility program is deeply integrated with the health system's other specialties — including oncology, urology, genetics, and maternal-fetal medicine — enabling seamless co-management of complex reproductive cases. The Midtown location is accessible from multiple subway lines and is central to New York's dense professional and residential communities. Patients exploring fertility options across the state can visit our guide to fertility clinics in New York.
Physicians and Clinical Team
NYU Langone's fertility team includes some of the most academically prominent reproductive endocrinologists in the United States. Dr. James Grifo, program director at NYU Langone Fertility, is widely regarded as a pioneer in IVF and preimplantation genetic testing, with publications dating back to the early years of PGT development in the 1990s. His work has directly influenced national and international protocols for chromosomal screening and embryo selection. Other faculty include Dr. Nicole Noyes, known for her work in oncofertility and fertility preservation, and additional REI faculty with expertise in donor egg, recurrent loss, and LGBTQ+ family building. All attending physicians hold faculty appointments at NYU Grossman School of Medicine and maintain board certification in REI. The academic environment supports fellow training, ongoing research, and participation in clinical trials.
Services and Treatments
- IVF — fresh and frozen embryo transfer
- Intrauterine insemination (IUI)
- Egg freezing (elective, oncofertility, and age-related)
- Embryo banking and cryopreservation
- Preimplantation genetic testing (PGT-A, PGT-M, PGT-SR)
- Donor egg IVF — in-house and agency coordination
- Donor sperm services
- Reciprocal IVF for same-sex female couples
- LGBTQ+ family building (all pathways)
- Gestational surrogacy coordination
- Male infertility evaluation and treatment, including micro-TESE coordination
- Recurrent pregnancy loss evaluation
- Fertility preservation for cancer patients (priority scheduling)
- In vitro maturation (IVM) in select cases
Laboratory and Success Rates
NYU Langone Fertility operates an accredited embryology laboratory at the 53rd Street location, benefiting from both clinical volume and the academic resources of the health system. The laboratory has historically been among the most active in New York City in terms of annual cycle volume, which supports consistent embryologist expertise and rigorous quality benchmarking. NYU was a pioneering center in preimplantation genetic testing, and the laboratory's PGT workflow reflects decades of refinement. The practice participates in full SART and CDC reporting. Academic-affiliated programs tend to treat a higher proportion of complex cases, which can affect aggregate success rate statistics relative to programs with a more straightforward patient mix. Patients should review the most current cycle-level data published by the CDC's ART Surveillance program and the SART Clinic Summary Report.
Patient Experience
The East 53rd Street location is two blocks from the Lexington Avenue subway corridor (E/M at 53rd St, 6 at 51st St), making it accessible from all boroughs without requiring a car. The facility occupies a dedicated floor within a modern Midtown office building, with separate spaces for consultations, monitoring, and procedures. Patients navigating IVF in New York City often comment that the logistics of monitoring appointments — getting to the clinic early in the morning before work — are made manageable by the subway-accessible location.
The integration with NYU Langone's health system means patients who require additional evaluation by urologists, oncologists, or maternal-fetal medicine specialists can be referred internally and have records shared within the Epic electronic health record. For patients with complex medical histories or active cancer diagnoses, this coordination is a significant practical advantage. The fertility center's patient portal provides 24/7 access to results and secure messaging, and telehealth options are available for consultations that do not require physical examination.
Considering At-Home Insemination?
Not every fertility journey begins in a clinic. At-home intracervical insemination (ICI) is a lower-cost, private option that suits patients with no known fertility diagnosis — including single parents by choice, same-sex couples, and people who want to try a few cycles before committing to clinical treatment.
At-home insemination kits like those from MakeAMom come with step-by-step instructions designed for donor or partner sperm. Kits are a one-time purchase that can be reused until conception succeeds, require no clinic visit, and arrive in plain, discreet packaging. Many patients use them as a first step while working toward a fertility consultation — or alongside ovulation tracking while they wait for an appointment slot.
If you have a known fertility diagnosis, have been trying for 12 months without success (six months if you're over 35), or your physician has already recommended IUI or IVF, a board-certified reproductive endocrinologist is the right next step.
Insurance and Financing
New York State requires large-group health insurance plans to cover IVF — up to three complete oocyte retrievals — for patients with a diagnosis of infertility, as well as fertility preservation for medical reasons. The mandate extends to same-sex couples on equal terms with heterosexual couples, consistent with New York's civil rights laws. NYU Langone's insurance team is experienced navigating the New York State mandate and can assist with prior authorization. Patients with self-funded ERISA plans or out-of-state insurance should confirm the applicability of their coverage. For patients without coverage, NYU Langone Fertility offers financing options and can connect patients with financial assistance resources including grants from fertility patient advocacy organizations.
Frequently Asked Questions
Is NYU Langone Fertility a research-focused program? Will I be treated by fellows? NYU Langone Fertility is an academic program with an REI fellowship training component. Attending physicians oversee all clinical care and perform procedures. Fellows participate in patient care under attending supervision, consistent with standard academic medical center practice. Many patients specifically choose academic programs for access to the latest evidence-based protocols and the clinical depth that comes with a highly active research environment.
Does NYU offer emergency fertility preservation for cancer patients? Yes. NYU Langone Fertility has a dedicated oncofertility program for patients who need egg or embryo freezing before starting chemotherapy, radiation, or surgery. Cases are prioritized for rapid consultation and expedited cycle start when clinically necessary. The fertility center coordinates directly with NYU's oncology teams to minimize delays in cancer treatment.
What LGBTQ+ family-building pathways are available? All pathways are available. Same-sex female couples can pursue reciprocal IVF or donor sperm IVF. Same-sex male couples can pursue gestational surrogacy with donor eggs. Single patients of any gender can access donor sperm or donor egg IVF. Transgender patients can access fertility preservation at any stage of gender-affirming care. Dedicated coordinators are available for LGBTQ+ family-building consultations.
How do I schedule a consultation at NYU Langone Fertility? Call (212) 263-8990 or use the NYU Langone online appointment request portal. New patient appointments at the 53rd Street location are typically available within a few weeks. Patients with urgent situations, including active cancer diagnoses, should identify themselves as such when scheduling to be triaged appropriately.